Dog dental care is often overlooked, yet it plays a major role in your dog’s overall health. Plaque buildup, bad breath, and gum disease can lead to serious issues if left untreated. Using the best toothpaste for dogs helps prevent tartar, freshens breath, and supports healthy gums — without the dangers of human toothpaste.
In this guide, we review 5 of the best dog toothpastes available on Amazon, focusing on safety, ingredients, effectiveness, and ease of use.
Best Toothpaste for Dogs – Quick Comparison
| Product | Best For | Formula Type |
|---|---|---|
| Virbac Enzymatic Toothpaste | Overall dental care | Enzymatic |
| Arm & Hammer Dog Toothpaste | Bad breath | Baking soda |
| Vet’s Best Dog Toothpaste | Natural ingredients | Herbal |
| Petrodex Enzymatic Toothpaste | Heavy plaque | Enzymatic |
| Nylabone Advanced Dental Gel | No-brush option | Gel |
1. Virbac C.E.T. Enzymatic Dog Toothpaste – Best Overall
Virbac C.E.T. Enzymatic Toothpaste is one of the most trusted dog dental products and is frequently recommended by veterinarians. It uses an enzymatic formula that helps break down plaque and reduce bacteria even after brushing is finished. This makes it especially effective for dogs that resist longer brushing sessions.

The toothpaste is fluoride-free and safe to swallow, which is essential because dogs do not rinse their mouths. It comes in dog-friendly flavors like poultry and beef, helping make brushing a more pleasant experience. The gentle formula is suitable for daily use and works well for dogs of all sizes and breeds.
With regular use, many dog owners notice improved breath, less plaque buildup, and healthier gums. This toothpaste works best when paired with a soft toothbrush or finger brush and used at least two to three times per week.
2. Arm & Hammer Enzymatic Dog Toothpaste – Best for Bad Breath
Arm & Hammer Enzymatic Dog Toothpaste is a popular option for dogs struggling with persistent bad breath. It contains baking soda, which naturally neutralizes odors and helps clean teeth. Combined with enzymes, it also assists in breaking down plaque and tartar over time.

This toothpaste is free from fluoride and safe for dogs to swallow. It comes in appealing flavors such as chicken or beef, making it easier to introduce into your dog’s routine. Many dog owners appreciate how quickly it freshens breath, sometimes after just a few uses.
While it is gentle enough for regular brushing, dogs with extremely sensitive gums should be introduced gradually. Used consistently, this toothpaste can significantly improve breath freshness and overall oral hygiene.
3. Vet’s Best Enzymatic Dog Toothpaste – Best Natural Formula
Vet’s Best Enzymatic Dog Toothpaste is ideal for pet owners who prefer natural ingredients. Its formula includes aloe vera, neem oil, grapefruit seed extract, and baking soda to help clean teeth while soothing gums.

The toothpaste is designed to reduce plaque and tartar buildup while freshening breath without harsh chemicals. It is safe to swallow and does not contain artificial colors or flavors. The mild taste makes it a good choice for dogs new to tooth brushing.
This toothpaste is especially suitable for dogs with sensitive mouths or minor gum irritation. While results may take a bit longer compared to stronger enzymatic formulas, consistent use can lead to healthier gums and cleaner teeth.
4. Petrodex Enzymatic Dog Toothpaste – Best for Heavy Plaque
Petrodex Enzymatic Dog Toothpaste is designed for dogs with significant plaque and tartar buildup. Its non-foaming enzymatic formula works to reduce bacteria and break down plaque efficiently.

The toothpaste is fluoride-free and safe for daily use. It comes in flavors like poultry, which helps improve compliance during brushing. Many dog owners see visible improvement in tartar reduction after a few weeks of consistent use.
This toothpaste is a strong option for adult and senior dogs that may already have dental issues. For best results, it should be paired with regular brushing and routine dental checkups.
5. Nylabone Advanced Oral Care Dental Gel – Best No-Brush Option
Nylabone Advanced Oral Care Dental Gel is perfect for dogs that refuse brushing. This gel is applied directly to the teeth and gums, where it works to reduce bacteria and freshen breath without brushing.

The formula is safe to swallow and does not contain alcohol or harmful chemicals. It is especially useful for anxious dogs or puppies still learning dental routines. While brushing is always more effective, this gel provides a convenient alternative for maintaining oral hygiene.
Used daily, it can help slow plaque buildup and keep your dog’s breath fresher between brushings.
How to Brush Your Dog’s Teeth Properly
- Use dog-specific toothpaste only
- Start with short sessions (30 seconds)
- Use a soft toothbrush or finger brush
- Brush 2–3 times per week (daily is ideal)
- No rinsing needed
Final Verdict: Is Dog Toothpaste Worth It?
Absolutely. Using the best toothpaste for dogs is one of the simplest ways to prevent dental disease, improve breath, and avoid costly vet bills. Choosing a safe, effective formula and using it consistently can greatly improve your dog’s quality of life.
Frequently Asked Questions
No. Human toothpaste often contains fluoride or xylitol, which are toxic to dogs.
Yes. Dog toothpaste is specifically formulated to be swallowed safely
At least 2–3 times per week; daily brushing gives the best results.

